prevalence assessment of maga gene and antimicrobial susceptibility of klebsiella pneumoniae isolated from clinical specimens in shahrekord, iran.
نویسندگان
چکیده
background and objectives: klebsiella pneumoniae ( k. pneumoniae ) is an opportunistic microorganism. this study aimed to investigate the presence of mag a gene and antimicrobial susceptibility in k. pneumoniae . materials and methods: 195 clinical specimens were collected from hospitals of shahrekord, iran. bacterial culture, biochemical diagnostic standard test, determination of antibiotic sensitivity, phenotypic testing hypermucoviscosity (hv) and polymerase chain reaction (pcr) was performed for isolation and characterization of k. pneumoniae . results: 173 samples were positive for k. pneumoniae . the highest and lowest rates of resistance were related to amoxicil-lin 79.19% and ciprofloxacin 15.60%, respectively. also 4 samples were positive for mag a gene. conclusion: based on our results, k. pneumoniae strains were resistant to different antibiotics. knowing how to identify strains of k. pneumoniae , spreading of its virulence and also antimicrobial resistance genes can be useful in treatment of infection caused by this bacterium.
منابع مشابه
Prevalence assessment of magA gene and antimicrobial susceptibility of Klebsiella pneumoniae isolated from clinical specimens in Shahrekord, Iran
BACKGROUND AND OBJECTIVES Klebsiella pneumoniae (K. pneumoniae) is an opportunistic microorganism. This study aimed to investigate the presence of magA gene and antimicrobial susceptibility in K. pneumoniae. MATERIALS AND METHODS clinical specimens were collected from hospitals of Shahrekord, Iran. Bacterial culture, biochemical diagnostic standard test, determination of antibiotic sensitivit...
متن کاملThe Prevalence of Carbapenemase Producing Klebsiella pneumoniae Strains Isolated from Clinical Urine Specimens in University Teaching Hospitals, Iran
Background and Aims: Klebsiella pneumoniae is a gram negative opportunistic pathogen of nosocomial infections that causes pneumonia, urinary tract infection (UTI), meningitis, septicemia and diarrhea. The emergence and spread of carbapenemase producing Klebsiella pneumoniae often cause failure in the treatment of infections. The aim of this study was to evaluate the prevalence of carbapenemase ...
متن کاملDetection of magA Gene in Klebsiella spp. Isolated from Clinical Samples
Objective(s): Klebsiella infections are caused mainly by K. pneumoniae and K. oxytoca. In the last two decades, a new type of invasive Klebsiella pneumoniae which contains mucoviscosity-associated gene (magA) has emerged. The aim of this study was to investigate the prevalence of magA gene and to detect antimicrobial susceptibility patterns of Klebsiella spp. isolated from clinical samples....
متن کاملPrevalence of qnr Genes in Extended-Spectrum β-Lactamase Producing Klebsiella pneumoniae Isolated from Clinical Urine Specimens in University Teaching Hospitals, Iran
Background and Aims: Extended-spectrum β-lactamase (ESBL) producing gram negative bacteria are resistant to penicillins, narrow and extended-spectrum cephalosporins, and aztreonam; also they are frequently resistant to trimethoprim-sulfamethoxazole, aminoglycosides, and quinolones. This study aimed to investigate the prevalence of plasmid-mediated quinolone resistance (PMQR) determinants q...
متن کاملDetection of magA Gene in Klebsiella spp. Isolated from Clinical SamplesDetection of magA
OBJECTIVE(S) Klebsiella infections are caused mainly by K. pneumoniae and K. oxytoca. In the last two decades, a new type of invasive Klebsiella pneumoniae which contains mucoviscosity-associated gene (magA) has emerged. The aim of this study was to investigate the prevalence of magA gene and to detect antimicrobial susceptibility patterns of Klebsiella spp. isolated from clinical samples. MA...
متن کاملPrevalence of Plasmid-Mediated Quinolones Resistance among Klebsiella pneumoniae Strains Isolated from Hospitals in Borujerd, Iran
ABSTRACT Background and Objective: Klebsiella pneumoniae is one of the most common causes of bacterial infections. Presence of plasmid-mediated quinolone resistance genes causes low level of resistance in K. pneumoniae. This study investigated the prevalence of resistance to quinolones and fluoroquinolones, and the frequency of qnrA, qnrB and qnrS genes amo...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of microbiologyجلد ۶، شماره ۵، صفحات ۳۱۱-۳۱۶
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023